MiR-27a Functions as a Tumor Suppressor in Acute Leukemia by Regulating 14-3-3θ

MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignancies. In this work, we report that miR-27a, and its coordinately expressed cluster (miR-23a∼miR-27a∼miR-24-2), was down-regulated in acute leukemia cell lines and primary samples compared to hematopoi...

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Detalles Bibliográficos
Autores principales: Scheibner, Kara A., Teaboldt, Brianne, Hauer, Mary Claire, Chen, Xiaochun, Cherukuri, Srujana, Guo, Yin, Kelley, Shannon M., Liu, Zhenqiu, Baer, Maria R., Heimfeld, Shelly, Civin, Curt I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517579/
https://www.ncbi.nlm.nih.gov/pubmed/23236401
http://dx.doi.org/10.1371/journal.pone.0050895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517579/
https://www.ncbi.nlm.nih.gov/pubmed/23236401
http://dx.doi.org/10.1371/journal.pone.0050895

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