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MiR-27a Functions as a Tumor Suppressor in Acute Leukemia by Regulating 14-3-3θ
MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignancies. In this work, we report that miR-27a, and its coordinately expressed cluster (miR-23a∼miR-27a∼miR-24-2), was down-regulated in acute leukemia cell lines and primary samples compared to hematopoi...
Autores principales: | Scheibner, Kara A., Teaboldt, Brianne, Hauer, Mary Claire, Chen, Xiaochun, Cherukuri, Srujana, Guo, Yin, Kelley, Shannon M., Liu, Zhenqiu, Baer, Maria R., Heimfeld, Shelly, Civin, Curt I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517579/ https://www.ncbi.nlm.nih.gov/pubmed/23236401 http://dx.doi.org/10.1371/journal.pone.0050895 |
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