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TNF-α Affects Human Cortical Neural Progenitor Cell Differentiation through the Autocrine Secretion of Leukemia Inhibitory Factor

Proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) is a crucial effector of immune responses in the brain that participates in the pathogenesis of several acute and chronic neurodegenerative disorders. Accumulating evidence has suggested that TNF-α negatively regulates embryonic and adult...

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Detalles Bibliográficos
Autores principales: Lan, Xiqian, Chen, Qiang, Wang, Yongxiang, Jia, Beibei, Sun, Lijun, Zheng, Jialin, Peng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517586/
https://www.ncbi.nlm.nih.gov/pubmed/23236394
http://dx.doi.org/10.1371/journal.pone.0050783