Different Characteristics and Nucleotide Binding Properties of Inosine Monophosphate Dehydrogenase (IMPDH) Isoforms

We recently reported that Inosine Monophosphate Dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, clustered into macrostructures in response to decreased nucleotide levels and that there were differences between the IMPDH isoforms, IMPDH1 and IMPDH2. We hypoth...

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Detalles Bibliográficos
Autores principales: Thomas, Elaine C., Gunter, Jennifer H., Webster, Julie A., Schieber, Nicole L., Oorschot, Viola, Parton, Robert G., Whitehead, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517587/
https://www.ncbi.nlm.nih.gov/pubmed/23236438
http://dx.doi.org/10.1371/journal.pone.0051096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517587/
https://www.ncbi.nlm.nih.gov/pubmed/23236438
http://dx.doi.org/10.1371/journal.pone.0051096

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