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Different Characteristics and Nucleotide Binding Properties of Inosine Monophosphate Dehydrogenase (IMPDH) Isoforms
We recently reported that Inosine Monophosphate Dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, clustered into macrostructures in response to decreased nucleotide levels and that there were differences between the IMPDH isoforms, IMPDH1 and IMPDH2. We hypoth...
Autores principales: | Thomas, Elaine C., Gunter, Jennifer H., Webster, Julie A., Schieber, Nicole L., Oorschot, Viola, Parton, Robert G., Whitehead, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517587/ https://www.ncbi.nlm.nih.gov/pubmed/23236438 http://dx.doi.org/10.1371/journal.pone.0051096 |
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