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Proteomic Investigations of Lysine Acetylation Identify Diverse Substrates of Mitochondrial Deacetylase Sirt3

Lysine acetylation is a posttranslational modification that is dynamically regulated by the activity of acetyltransferases and deacetylases. The human and mouse genomes encode 18 different lysine deacetylases (KDACs) which are key regulators of many cellular processes. Identifying substrates of KDAC...

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Detalles Bibliográficos
Autores principales: Sol, Eri Maria, Wagner, Sebastian A., Weinert, Brian T., Kumar, Amit, Kim, Hyun-Seok, Deng, Chu-Xia, Choudhary, Chunaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517600/
https://www.ncbi.nlm.nih.gov/pubmed/23236377
http://dx.doi.org/10.1371/journal.pone.0050545