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Proteomic Investigations of Lysine Acetylation Identify Diverse Substrates of Mitochondrial Deacetylase Sirt3
Lysine acetylation is a posttranslational modification that is dynamically regulated by the activity of acetyltransferases and deacetylases. The human and mouse genomes encode 18 different lysine deacetylases (KDACs) which are key regulators of many cellular processes. Identifying substrates of KDAC...
Autores principales: | Sol, Eri Maria, Wagner, Sebastian A., Weinert, Brian T., Kumar, Amit, Kim, Hyun-Seok, Deng, Chu-Xia, Choudhary, Chunaram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517600/ https://www.ncbi.nlm.nih.gov/pubmed/23236377 http://dx.doi.org/10.1371/journal.pone.0050545 |
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