Chiral Ruthenium(II) Polypyridyl Complexes: Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Cellular Uptake

Two ruthenium(II) complexes, Λ-[Ru(phen)(2)(p-HPIP)](2+) and Δ-[Ru(phen)(2)(p-HPIP)](2+), were synthesized and characterized via proton nuclear magnetic resonance spectroscopy, electrospray ionization-mass spectrometry, and circular dichroism spectroscopy. This study aims to clarify the anticancer e...

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Detalles Bibliográficos
Autores principales: Yu, Qianqian, Liu, Yanan, Wang, Chuan, Sun, Dongdong, Yang, Xingcheng, Liu, Yanyu, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517606/
https://www.ncbi.nlm.nih.gov/pubmed/23236402
http://dx.doi.org/10.1371/journal.pone.0050902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517606/
https://www.ncbi.nlm.nih.gov/pubmed/23236402
http://dx.doi.org/10.1371/journal.pone.0050902

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