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Surfactant Protein A in Cystic Fibrosis: Supratrimeric Structure and Pulmonary Outcome

BACKGROUND: The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A’s functional properties and could thereby influence clinical status in patients with lung diseases. In this study we focus on SP-A structure in cystic fib...

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Detalles Bibliográficos
Autores principales: Griese, Matthias, Heinrich, Stephanie, Ratjen, Felix, Kabesch, Michael, Paul, Karl, Ballmann, Manfred, Rietschel, Ernst, Kappler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517609/
https://www.ncbi.nlm.nih.gov/pubmed/23236429
http://dx.doi.org/10.1371/journal.pone.0051050