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Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs

Fatty acid binding proteins (FABPs), in particular FABP5 and FABP7, have recently been identified by us as intracellular transporters for the endocannabinoid anandamide (AEA). Furthermore, animal studies by others have shown that elevated levels of endocannabinoids resulted in beneficial pharmacolog...

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Detalles Bibliográficos
Autores principales: Berger, William T., Ralph, Brian P., Kaczocha, Martin, Sun, Jing, Balius, Trent E., Rizzo, Robert C., Haj-Dahmane, Samir, Ojima, Iwao, Deutsch, Dale G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517626/
https://www.ncbi.nlm.nih.gov/pubmed/23236415
http://dx.doi.org/10.1371/journal.pone.0050968