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Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer

BACKGROUND: Cancer is an extremely heterogeneous group of diseases traditionally categorized according to tissue of origin. However, even among patients with the same cancer subtype the cellular alterations at the molecular level are often very different. Several new therapies targeting specific mol...

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Detalles Bibliográficos
Autores principales: Kristensen, Lasse Sommer, Kjeldsen, Tina Ellegaard, Hager, Henrik, Hansen, Lise Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517778/
https://www.ncbi.nlm.nih.gov/pubmed/23173730
http://dx.doi.org/10.1186/1471-2407-12-548