Stimulation of Adrenal Chromaffin Cell Proliferation by Hypercalcemia Induced by Intravenous Infusion of Calcium Gluconate in Rats

Increased incidence of adrenal pheochromocytoma is frequently encountered in rat carcinogenicity studies. In some of the studies, the finding is judged to be due to a rat-specific mechanism of carcinogenesis caused by a disturbance of calcium homeostasis. However, direct evidence that the proliferat...

Descripción completa

Detalles Bibliográficos
Autores principales: Isobe, Kaori, Ito, Tsuneo, Komatsu, Shun-ichiro, Asanuma, Kentaro, Fujii, Etsuko, Kato, Chie, Adachi, Kenji, Kato, Atsuhiko, Sugimoto, Tetsuro, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517925/
https://www.ncbi.nlm.nih.gov/pubmed/23345932
http://dx.doi.org/10.1293/tox.25.281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517925/
https://www.ncbi.nlm.nih.gov/pubmed/23345932
http://dx.doi.org/10.1293/tox.25.281

Ejemplares similares