Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion

Lifelong blood cell production is governed through the poorly understood integration of cell-intrinsic and -extrinsic control of hematopoietic stem cell (HSC) quiescence and activation. MicroRNAs (miRNAs) coordinately regulate multiple targets within signaling networks, making them attractive candid...

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Detalles Bibliográficos
Autores principales: Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517970/
https://www.ncbi.nlm.nih.gov/pubmed/23142521
http://dx.doi.org/10.1016/j.stem.2012.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517970/
https://www.ncbi.nlm.nih.gov/pubmed/23142521
http://dx.doi.org/10.1016/j.stem.2012.09.001

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