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Bonding the foe – NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals

In the presence of sodium, uric acid from purine metabolism precipitates as monosodium urate (MSU) needles and forms renal calculi or causes gouty arthritis in kidneys and joints, respectively. The latter is characterized by red, hot, and swollen arthritic joints. Here we report the in vitro effect...

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Detalles Bibliográficos
Autores principales: Schorn, Christine, Janko, Christina, Krenn, Veit, Zhao, Yi, Munoz, Luis E., Schett, Georg, Herrmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517988/
https://www.ncbi.nlm.nih.gov/pubmed/23233855
http://dx.doi.org/10.3389/fimmu.2012.00376