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Bonding the foe – NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals
In the presence of sodium, uric acid from purine metabolism precipitates as monosodium urate (MSU) needles and forms renal calculi or causes gouty arthritis in kidneys and joints, respectively. The latter is characterized by red, hot, and swollen arthritic joints. Here we report the in vitro effect...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517988/ https://www.ncbi.nlm.nih.gov/pubmed/23233855 http://dx.doi.org/10.3389/fimmu.2012.00376 |