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In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma

BACKGROUND: Metformin, which is widely used as an antidiabetic agent, has recently been reported to reduce cancer risk and improve prognosis in certain malignancies. However, the specific mechanisms underlying the effect of metformin on the development and progression of several cancers including or...

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Detalles Bibliográficos
Autores principales: Luo, Qingqiong, Hu, Dan, Hu, Shuiqing, Yan, Ming, Sun, Zujun, Chen, Fuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518152/
https://www.ncbi.nlm.nih.gov/pubmed/23151022
http://dx.doi.org/10.1186/1471-2407-12-517