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Munc13 controls the location and efficiency of dense-core vesicle release in neurons
Neuronal dense-core vesicles (DCVs) contain diverse cargo crucial for brain development and function, but the mechanisms that control their release are largely unknown. We quantified activity-dependent DCV release in hippocampal neurons at single vesicle resolution. DCVs fused preferentially at syna...
Autores principales: | van de Bospoort, Rhea, Farina, Margherita, Schmitz, Sabine K., de Jong, Arthur, de Wit, Heidi, Verhage, Matthijs, Toonen, Ruud F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518216/ https://www.ncbi.nlm.nih.gov/pubmed/23229896 http://dx.doi.org/10.1083/jcb.201208024 |
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