Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells

In this paper, we describe how a dynamic regulatory process is necessary to restrict microvilli to the apical aspect of polarized epithelial cells. We found that local phosphocycling regulation of ezrin, a critical plasma membrane–cytoskeletal linker of microvilli, was required to restrict its funct...

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Detalles Bibliográficos
Autores principales: Viswanatha, Raghuvir, Ohouo, Patrice Y., Smolka, Marcus B., Bretscher, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518218/
https://www.ncbi.nlm.nih.gov/pubmed/23209304
http://dx.doi.org/10.1083/jcb.201207047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518218/
https://www.ncbi.nlm.nih.gov/pubmed/23209304
http://dx.doi.org/10.1083/jcb.201207047

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