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Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells
In this paper, we describe how a dynamic regulatory process is necessary to restrict microvilli to the apical aspect of polarized epithelial cells. We found that local phosphocycling regulation of ezrin, a critical plasma membrane–cytoskeletal linker of microvilli, was required to restrict its funct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518218/ https://www.ncbi.nlm.nih.gov/pubmed/23209304 http://dx.doi.org/10.1083/jcb.201207047 |