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KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression

The small GTPase Rap1 regulates inside-out integrin activation and thereby influences cell adhesion, migration, and polarity. Several Rap1 effectors have been described to mediate the cellular effects of Rap1 in a context-dependent manner. Radil is emerging as an important Rap effector implicated in...

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Detalles Bibliográficos
Autores principales: Ahmed, Syed M., Thériault, Brigitte L., Uppalapati, Maruti, Chiu, Catherine W.N., Gallie, Brenda L., Sidhu, Sachdev S., Angers, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518219/
https://www.ncbi.nlm.nih.gov/pubmed/23209302
http://dx.doi.org/10.1083/jcb.201206051