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Linking abnormal mitosis to the acquisition of DNA damage

Cellular defects that impair the fidelity of mitosis promote chromosome missegregation and aneuploidy. Increasing evidence reveals that errors in mitosis can also promote the direct and indirect acquisition of DNA damage and chromosome breaks. Consequently, deregulated cell division can devastate th...

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Detalles Bibliográficos
Autores principales: Ganem, Neil J., Pellman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518222/
https://www.ncbi.nlm.nih.gov/pubmed/23229895
http://dx.doi.org/10.1083/jcb.201210040