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Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
Telomeres in cells that use the recombination-mediated alternative lengthening of telomeres (ALT) pathway elicit a DNA damage response that is partly independent of telomere length. We therefore investigated whether ALT telomeres contain structural abnormalities that contribute to ALT activity. Here...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518223/ https://www.ncbi.nlm.nih.gov/pubmed/23229897 http://dx.doi.org/10.1083/jcb.201207189 |