Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells

Telomeres in cells that use the recombination-mediated alternative lengthening of telomeres (ALT) pathway elicit a DNA damage response that is partly independent of telomere length. We therefore investigated whether ALT telomeres contain structural abnormalities that contribute to ALT activity. Here...

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Detalles Bibliográficos
Autores principales: Conomos, Dimitri, Stutz, Michael D., Hills, Mark, Neumann, Axel A., Bryan, Tracy M., Reddel, Roger R., Pickett, Hilda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518223/
https://www.ncbi.nlm.nih.gov/pubmed/23229897
http://dx.doi.org/10.1083/jcb.201207189

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