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Differential baseline expression and angiotensin II–stimulation of leukemia-associated RhoGEF in vascular smooth muscle cells of spontaneously hypertensive rats

PURPOSE: Studies to explore angiotensin II (Ang II) and its downstream signaling pathways via Rho guanine nucleotide exchange factors (RhoGEFs) and RhoA signaling are crucial to understanding the mechanisms of smooth muscle contraction leading to hypertension. This study aimed to investigate the Ang...

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Detalles Bibliográficos
Autores principales: Chiu, Wei-Chiao, Juang, Jyh-ming, Chang, Shen-nan, Wu, Cho-kai, Tsai, Chia-ti, Tseng, Chuen-den, Tseng, Yung-zu, Su, Ming-Jai, Chiang, Fu-tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518287/
https://www.ncbi.nlm.nih.gov/pubmed/23233801
http://dx.doi.org/10.2147/IJN.S36700