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MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies. Recent studies suggest that microRNAs (miRNAs) play an essential role in immunoregulation and may be involved in the pathogenesis of SLE. Therefore, it was of in...

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Detalles Bibliográficos
Autores principales: Pan, Yang, Jia, Tingting, Zhang, Yuan, Zhang, Kuo, Zhang, Rui, Li, Jinming, Wang, Lunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518289/
https://www.ncbi.nlm.nih.gov/pubmed/23233803
http://dx.doi.org/10.2147/IJN.S37990