Fast and ultrasensitive method for quantitating prion infectivity titer

Bioassay by end-point dilution has been employed for decades for routine determination of prion infectivity titer. Here we show that the new Protein Misfolding Cyclic Amplification with Teflon beads (PMCAb) can be used to estimate titers of the misfolded version of the prion protein (PrP(Sc)) with a...

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Detalles Bibliográficos
Autores principales: Makarava, Natallia, Savtchenko, Regina, Alexeeva, Irina, Rohwer, Robert G., Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518416/
https://www.ncbi.nlm.nih.gov/pubmed/22415832
http://dx.doi.org/10.1038/ncomms1730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518416/
https://www.ncbi.nlm.nih.gov/pubmed/22415832
http://dx.doi.org/10.1038/ncomms1730

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