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Fast and ultrasensitive method for quantitating prion infectivity titer
Bioassay by end-point dilution has been employed for decades for routine determination of prion infectivity titer. Here we show that the new Protein Misfolding Cyclic Amplification with Teflon beads (PMCAb) can be used to estimate titers of the misfolded version of the prion protein (PrP(Sc)) with a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518416/ https://www.ncbi.nlm.nih.gov/pubmed/22415832 http://dx.doi.org/10.1038/ncomms1730 |