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Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice

The ARF locus is frequently inactivated in human cancer. The oncosuppressor ARF has indeed been described as a general sensor for different situation of cellular stress. We have previously demonstrated that ARF deficiency severely impairs inflammatory responses in vitro and in vivo, establishing a r...

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Detalles Bibliográficos
Autores principales: Herranz, Sandra, Través, Paqui G., Luque, Alfonso, Hortelano, Sonsoles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518495/
https://www.ncbi.nlm.nih.gov/pubmed/23243586
http://dx.doi.org/10.4161/onci.21207