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Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy
A decade of collective work by tumor immunologists has led to improved large scale generation, maturation, antigen loading and administration of dendritic cells (DCs) to cancer patients, promoting enhanced antitumor activity. We alleviated the HLA-restriction in DC therapy and demonstrated that it i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518513/ https://www.ncbi.nlm.nih.gov/pubmed/23243604 http://dx.doi.org/10.4161/onci.20926 |