Cargando…

Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer

An intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor MCPyV status. Hence, boo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sihto, Harri, Joensuu, Heikki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518523/ https://www.ncbi.nlm.nih.gov/pubmed/23243614 http://dx.doi.org/10.4161/onci.21120

Ejemplares similares

Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy
por: Loi, Sherene
Publicado: (2013)

The antigen specific composition of melanoma tumor infiltrating lymphocytes?
por: Hadrup, Sine Reker
Publicado: (2012)

Tumor-infiltrating lymphocytes in breast cancer: A new predictor for responses to therapy
por: Issa-Nummer, Yasmin, et al.
Publicado: (2014)

Won’t you come on in? How to favor lymphocyte infiltration in tumors
por: Bellone, Matteo, et al.
Publicado: (2012)

Distribution, function and predictive value of tumor-infiltrating γδ T lymphocytes
por: Dieli, Francesco, et al.
Publicado: (2013)

Tumor high endothelial venules (HEVs) predict lymphocyte infiltration and favorable prognosis in breast cancer
por: Martinet, Ludovic, et al.
Publicado: (2012)

Replenish the source within: Rescuing tumor-infiltrating lymphocytes by double checkpoint blockade
por: Duraiswamy, Jaikumar, et al.
Publicado: (2013)

Sugars boost exhausted tumor-infiltrating lymphocytes by counteracting immunosuppressive activities of galectins
por: Gordon-Alonso, Monica, et al.
Publicado: (2014)

Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
por: Martinet, Ludovic, et al.
Publicado: (2013)

PD-L1 expression and tumor-infiltrating lymphocytes: Revisiting the antitumor immune response potential in breast cancer
por: Schalper, Kurt A
Publicado: (2014)

Prokineticins and Merkel cell polyomavirus infection in Merkel cell carcinoma
por: Lauttia, S, et al.
Publicado: (2014)

Tumor infiltration by chemokine receptor 7 (CCR7)(+) T-lymphocytes is a favorable prognostic factor in metastatic colorectal cancer
por: Correale, Pierpaolo, et al.
Publicado: (2012)

Location, location, location: CD103 demarcates intraepithelial, prognostically favorable CD8(+) tumor-infiltrating lymphocytes in ovarian cancer
por: Webb, John R, et al.
Publicado: (2014)

CD8(+) T lymphocytes infiltrating breast cancer: A promising new prognostic marker?
por: Mahmoud, Sahar, et al.
Publicado: (2012)

Chronic lymphocytic leukaemia patients have a high risk of Merkel-cell polyomavirus DNA-positive Merkel-cell carcinoma
por: Koljonen, V, et al.
Publicado: (2009)

Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy
por: Chacon, Jessica Ann, et al.
Publicado: (2013)

Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
por: Wimmers, Florian, et al.
Publicado: (2014)

Tumor-infiltrating B cells: The ignored players in tumor immunology
por: Linnebacher, Michael, et al.
Publicado: (2012)

Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis
por: Hirt, Christian, et al.
Publicado: (2013)

Tumor-infiltrating follicular helper T cells: The new kids on the block
por: Gu-Trantien, Chunyan, et al.
Publicado: (2013)

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis
por: Labidi-Galy, Sana Intidhar, et al.
Publicado: (2012)

Know thy enemy: Why are tumor-infiltrating regulatory T cells so deleterious?
por: Facciabene, Andrea, et al.
Publicado: (2012)

Tumor-infiltrating B cells and T cells: Working together to promote patient survival
por: Nielsen, Julie S., et al.
Publicado: (2012)

Engineered tumor-infiltrating macrophages as gene delivery vehicles for interferon-α activates immunity and inhibits breast cancer progression
por: Escobar, Giulia, et al.
Publicado: (2014)

Oncogenic Merkel Cell Polyomavirus T Antigen Truncating Mutations are Mediated by APOBEC3 Activity in Merkel Cell Carcinoma
por: Soikkeli, Anni I., et al.
Publicado: (2022)

Lymphocyte-polarized DC1s: Effective inducers of tumor-specific CTLs
por: Berk, Erik, et al.
Publicado: (2012)

T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment
por: Pedroza-Gonzalez, Alexander, et al.
Publicado: (2013)

SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-α4
por: Carmona-Rodríguez, Lorena, et al.
Publicado: (2020)

The role of tumor expression of CD200 in tumor formation, metastasis and susceptibility to T lymphocyte adoptive transfer therapy
por: Talebian, Fatemeh, et al.
Publicado: (2012)

LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers
por: Sundqvist, Benjamin, et al.
Publicado: (2021)

The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration
por: Watt, Jennifer, et al.
Publicado: (2013)

Cytotoxic T lymphocytes: Sniping cancer stem cells
por: Hirohashi, Yoshihiko, et al.
Publicado: (2012)

ALK is frequently phosphorylated in Merkel cell carcinoma and associates with longer survival
por: Jaatinen, Jenni, et al.
Publicado: (2021)

Recruitment of γδ T lymphocytes to tumors: A new role for the pleiotropic chemokine CCL2
por: Lança, Telma, et al.
Publicado: (2013)

History of chronic inflammatory disorders increases the risk of Merkel cell carcinoma, but does not correlate with Merkel cell polyomavirus infection
por: Sahi, Helka, et al.
Publicado: (2017)

Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells
por: Liang, Hua, et al.
Publicado: (2013)

The immunological profile of tumor-bearing animals determines the outcome of cancer immunotherapy
por: Quetglas, José I, et al.
Publicado: (2013)

Virus infections in tumors pave the way for tumor-directed DC-vaccines
por: Woller, Norman, et al.
Publicado: (2012)

Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
por: Heinemann, Anja, et al.
Publicado: (2012)

Targeting the epigenetic addiction of Merkel cell carcinoma
por: Mauri, Federico, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pir0654j9f0huqvljdbf19foq5