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Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer

An intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor MCPyV status. Hence, boo...

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Detalles Bibliográficos
Autores principales: Sihto, Harri, Joensuu, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518523/
https://www.ncbi.nlm.nih.gov/pubmed/23243614
http://dx.doi.org/10.4161/onci.21120