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HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates
Constitutively stabilized HSP90 client proteins are crucial for cancer cell survival and proliferation. Thus, despite—or perhaps because of—their pleiotropic effects on variety of critical oncoproteins, HSP90 inhibitors represent a promising new class of anticancer drugs. We identified MIF as an ess...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518525/ https://www.ncbi.nlm.nih.gov/pubmed/23243616 http://dx.doi.org/10.4161/onci.21173 |