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Host gene-encoded severe lung TB: from genes to potential pathways

We are reporting that the two-locus genotype -2518 MCP-1 GG -1607 MMP-1 2G/2G promotes the expression of hyper-inflammation in response to M. tuberculosis infection, inducing extensive tissue damage and severe TB disease. Carriers of this two-locus genotype have a 13-fold higher chance of developing...

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Detalles Bibliográficos
Autores principales:	Ganachari, Malathesha, Guio, Heinner, Zhao, Nianxi, Flores-Villanueva, Pedro O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518758/ https://www.ncbi.nlm.nih.gov/pubmed/22992722 http://dx.doi.org/10.1038/gene.2012.39

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