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Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction
Hearing and balance use hair cells in the inner ear to transform mechanical stimuli into electrical signals(1). Mechanical force from sound waves or head movements is conveyed to hair-cell transduction channels by tip links(2,3), fine filaments formed by two atypical cadherins: protocadherin-15 and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518760/ https://www.ncbi.nlm.nih.gov/pubmed/23135401 http://dx.doi.org/10.1038/nature11590 |