Cargando…

B(12) cofactors directly stabilize an mRNA regulatory switch

Structures of riboswitch receptor domains bound to their effector have revealed how mRNAs recognize diverse small molecules, but mechanistic details into its linkage with regulation of gene expression remain elusive(1,2). To address this, we solved crystal structures of two different classes of coba...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, James E., Reyes, Francis E., Polaski, Jacob T., Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518761/
https://www.ncbi.nlm.nih.gov/pubmed/23064232
http://dx.doi.org/10.1038/nature11607