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B(12) cofactors directly stabilize an mRNA regulatory switch
Structures of riboswitch receptor domains bound to their effector have revealed how mRNAs recognize diverse small molecules, but mechanistic details into its linkage with regulation of gene expression remain elusive(1,2). To address this, we solved crystal structures of two different classes of coba...
Autores principales: | Johnson, James E., Reyes, Francis E., Polaski, Jacob T., Batey, Robert T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518761/ https://www.ncbi.nlm.nih.gov/pubmed/23064232 http://dx.doi.org/10.1038/nature11607 |
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