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Evolving role of 2B4/CD244 in T and NK cell responses during virus infection

The signaling lymphocyte activation molecule (SLAM) family receptor, 2B4/CD244, was first implicated in anti-viral immunity by the discovery that mutations of the SLAM-associated protein, SAP/SH2D1A, impaired 2B4-dependent stimulation of T and natural killer (NK) cell anti-viral functions in X-linke...

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Detalles Bibliográficos
Autores principales: Waggoner, Stephen N., Kumar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518765/
https://www.ncbi.nlm.nih.gov/pubmed/23248626
http://dx.doi.org/10.3389/fimmu.2012.00377