Centenarians, but not octogenarians, up-regulate the expression of microRNAs

Centenarians exhibit extreme longevity and a remarkable compression of morbidity. They have a unique capacity to maintain homeostatic mechanisms. Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may...

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Detalles Bibliográficos
Autores principales: Serna, Eva, Gambini, Juan, Borras, Consuelo, Mohammed, Kheira, Belenguer, Angel, Sanchis, Paula, Avellana, Juan A., Rodriguez-Mañas, Leocadio, Viña, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518811/
https://www.ncbi.nlm.nih.gov/pubmed/23233880
http://dx.doi.org/10.1038/srep00961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518811/
https://www.ncbi.nlm.nih.gov/pubmed/23233880
http://dx.doi.org/10.1038/srep00961

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