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Centenarians, but not octogenarians, up-regulate the expression of microRNAs
Centenarians exhibit extreme longevity and a remarkable compression of morbidity. They have a unique capacity to maintain homeostatic mechanisms. Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may...
Autores principales: | Serna, Eva, Gambini, Juan, Borras, Consuelo, Mohammed, Kheira, Belenguer, Angel, Sanchis, Paula, Avellana, Juan A., Rodriguez-Mañas, Leocadio, Viña, Jose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518811/ https://www.ncbi.nlm.nih.gov/pubmed/23233880 http://dx.doi.org/10.1038/srep00961 |
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