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Close Monitoring of Hepatitis B Surface Antigen Levels Helps Classify Flares During Peginterferon Therapy and Predicts Treatment Response

Background. Alanine aminotransferase (ALT) flares occur frequently during peginterferon (PEG-IFN) therapy. We related occurrence of flares to presence of precore (PC) and/or basal core promoter (BCP) mutants and studied kinetics of hepatitis B e antigen (HBeAg) and hepatitis B surface antigen (HBsAg...

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Detalles Bibliográficos
Autores principales: Sonneveld, Milan J., Zoutendijk, Roeland, Flink, Hajo J., Zwang, Louwerens, Hansen, Bettina E., Janssen, Harry L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518882/
https://www.ncbi.nlm.nih.gov/pubmed/23042976
http://dx.doi.org/10.1093/cid/cis859