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Effect of mycobacterial secretory proteins on the cellular integrity and cytokine profile of type II alveolar epithelial cells

BACKGROUND: Pulmonary tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tb). In lungs, alveolar macrophages and type II alveolar epithelial cells serve as a replicative niche for this pathogen. Secretory proteins released by actively replicating tubercle bacilli are known to interact wit...

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Detalles Bibliográficos
Autores principales: Adlakha, Nidhi, Vir, Pooja, Verma, Indu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519014/
https://www.ncbi.nlm.nih.gov/pubmed/23243342
http://dx.doi.org/10.4103/0970-2113.102796