Calcineurin activation causes retinal ganglion cell degeneration

PURPOSE: We previously reported that calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular hypertension models. In this study, we tested whether calcineurin activation by i...

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Detalles Bibliográficos
Autores principales: Qu, Juan, Matsouaka, Roland, Betensky, Rebecca A., Hyman, Bradley T., Grosskreutz, Cynthia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519372/
https://www.ncbi.nlm.nih.gov/pubmed/23233785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519372/
https://www.ncbi.nlm.nih.gov/pubmed/23233785

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