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Association of Mitochondrial DNA Polymerase γ Gene POLG1 Polymorphisms with Parkinsonism in Chinese Populations

BACKGROUND: Mitochondrial DNA polymerase gamma (POLG1) mutations were associated with levodopa-responsive Parkinsonism. POLG1 gene contains a number of common nonsynonymous SNPs and intronic regulatory SNPs which may have functional consequences. It is of great interest to discover polymorphisms var...

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Detalles Bibliográficos
Autores principales: Gui, Ya-xing, Xu, Zhong-ping, Lv, Wen, Liu, Hong-mei, Zhao, Jin-Jia, Hu, Xing-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519471/
https://www.ncbi.nlm.nih.gov/pubmed/23251356
http://dx.doi.org/10.1371/journal.pone.0050086