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Docetaxel-Resistance in Prostate Cancer: Evaluating Associated Phenotypic Changes and Potential for Resistance Transfer via Exosomes

BACKGROUND: Hormone-refractory prostate cancer remains hindered by inevitable progression of resistance to first-line treatment with docetaxel. Recent studies suggest that phenotypic changes associated with cancer may be transferred from cell-to-cell via microvesicles/exosomes. Here we aimed to inve...

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Detalles Bibliográficos
Autores principales: Corcoran, Claire, Rani, Sweta, O’Brien, Keith, O’Neill, Amanda, Prencipe, Maria, Sheikh, Rizwan, Webb, Glenn, McDermott, Ray, Watson, William, Crown, John, O’Driscoll, Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519481/
https://www.ncbi.nlm.nih.gov/pubmed/23251413
http://dx.doi.org/10.1371/journal.pone.0050999