Direct and Inverted Repeats Elicit Genetic Instability by Both Exploiting and Eluding DNA Double-Strand Break Repair Systems in Mycobacteria

Repetitive DNA sequences with the potential to form alternative DNA conformations, such as slipped structures and cruciforms, can induce genetic instability by promoting replication errors and by serving as a substrate for DNA repair proteins, which may lead to DNA double-strand breaks (DSBs). Howev...

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Detalles Bibliográficos
Autores principales: Wojcik, Ewelina A., Brzostek, Anna, Bacolla, Albino, Mackiewicz, Pawel, Vasquez, Karen M., Korycka-Machala, Malgorzata, Jaworski, Adam, Dziadek, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519483/
https://www.ncbi.nlm.nih.gov/pubmed/23251422
http://dx.doi.org/10.1371/journal.pone.0051064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519483/
https://www.ncbi.nlm.nih.gov/pubmed/23251422
http://dx.doi.org/10.1371/journal.pone.0051064

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