Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing

A challenge of systems biology is to integrate incomplete knowledge on pathways with existing experimental data sets and relate these to measured phenotypes. Research on ageing often generates such incomplete data, creating difficulties in integrating RNA expression with information about biological...

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Detalles Bibliográficos
Autores principales: Papatheodorou, Irene, Ziehm, Matthias, Wieser, Daniela, Alic, Nazif, Partridge, Linda, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519537/
https://www.ncbi.nlm.nih.gov/pubmed/23251396
http://dx.doi.org/10.1371/journal.pone.0050881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519537/
https://www.ncbi.nlm.nih.gov/pubmed/23251396
http://dx.doi.org/10.1371/journal.pone.0050881

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