Expression of Mutant Huntingtin in Leptin Receptor-Expressing Neurons Does Not Control the Metabolic and Psychiatric Phenotype of the BACHD Mouse

Metabolic and psychiatric disturbances occur early on in the clinical manifestation of Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin (HTT) gene. Hypothalamus has emerged as an important site of pathology and alterations in this area and it...

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Detalles Bibliográficos
Autores principales: Lundh, Sofia Hult, Soylu, Rana, Petersén, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519539/
https://www.ncbi.nlm.nih.gov/pubmed/23251447
http://dx.doi.org/10.1371/journal.pone.0051168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519539/
https://www.ncbi.nlm.nih.gov/pubmed/23251447
http://dx.doi.org/10.1371/journal.pone.0051168

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