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Adeno-Associated Virus Vector Mediated Expression of an Oncogenic Retroviral Envelope Protein Induces Lung Adenocarcinomas in Immunocompetent Mice

Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate of 16% necessitates the need for novel treatment strategies. Mouse models of lung cancer are important tools for analyzing the significance of somatic mutations in the initiation and progression of l...

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Detalles Bibliográficos
Autores principales: Linnerth-Petrik, Nicolle M., Santry, Lisa A., Yu, Darrick L., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519541/
https://www.ncbi.nlm.nih.gov/pubmed/23251519
http://dx.doi.org/10.1371/journal.pone.0051400