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miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells

BACKGROUND: Androgen receptor (AR) signalling is critical to the initiation and progression of prostate cancer (PCa). Transcriptional activity of AR involves chromatin recruitment of co-activators, including the p300/CBP-associated factor (PCAF). Distinct miRNA expression profiles have been identifi...

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Detalles Bibliográficos
Autores principales: Gong, Ai-Yu, Eischeid, Alex N, Xiao, Jing, Zhao, Jian, Chen, Dongqing, Wang, Zhao-Yi, Young, Charles YF, Chen, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519561/
https://www.ncbi.nlm.nih.gov/pubmed/23095762
http://dx.doi.org/10.1186/1471-2407-12-492