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Vaccination with a BCG Strain Overexpressing Ag85B Protects Cattle against Mycobacterium bovis Challenge

Mycobacterium bovis is the causative agent of tuberculosis in cattle but also infects other animals, including humans. Previous studies in cattle have demonstrated that the protection induced by BCG is not complete. In order to improve the protection efficacy of BCG, in this study we overexpressed A...

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Detalles Bibliográficos
Autores principales: Rizzi, Caroline, Bianco, María Verónica, Blanco, Federico Carlos, Soria, Marcelo, Gravisaco, María José, Montenegro, Valeria, Vagnoni, Lucas, Buddle, Bryce, Garbaccio, Sergio, Delgado, Fernando, Leal, Karen Silva, Cataldi, Angel Adrián, Dellagostin, Odir Antônio, Bigi, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519572/
https://www.ncbi.nlm.nih.gov/pubmed/23251517
http://dx.doi.org/10.1371/journal.pone.0051396